Prolactemia & Erectile Dysfunction w/ These Meds?
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Q:  Prolactemia & Erectile Dysfunction w/ These Meds?

I am 48 years old and have Bipolar Type I mixed episodes (296.60). Currently, I am taking 2500 mg of Depakote ER; 300 mg of Effexor XR; 50 mg Lamictal; 10 mg Abilify; and 75 mcg Cytomel.

I have had a lot of problems with prolactemia and erectile dysfunction while trying various atypical antipsychotics. This has been very frustrating.

Does abilify or any other drug I am taking cause prolactemia or other medical problem that would cause erectile dysfunction or should I be talking with a urologist.

Thank you.

Dear Mr. E' -- 
That much Depakote might do it; your blood level might yield a clue, if over 125 (our new "upper limit").  Effexor is certainly famous, along with almost all the other antidepressants that affect serotonin, for causing problems with sexual performance (everything from desire to erections to enjoyment and ejaculation); it's the most obvious candidate on this list.  We don't have enough experience with Abilify to say for sure, I don't think, yet, though this has not been a very prominent problem with that medication yet.  However, we don't have to invoke prolactin problems to explain this.  The Effexor alone is enough.  

Dr. Phelps

Published April, 2004


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