The Antipsychotics Leave Me with Little to No Motivation
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Q:  The Antipsychotics Leave Me with Little to No Motivation

I am in a catch 22. I take the antipsychotics, and they make me so  unmotivated I can t even take a shower, cook, or clean my house. I heard this is due to dopamine blockage --a motivator chemical).I have bipolar, and without them I am always depressed, and occasionally get mania & psychosis. I tried the antidepressant-mood stabilizer combo for a number of years, and did not find anything that worked. I am going to visit my bf in Oregon soon, and I am sure I will be embarrassed because I have a hard time even taking a shower. I cant stand this.  One doctor added Wellbutrin as some people get more energy with it, but it's not working. I'm so tempted to quit them, but I know I will land right back in the hospital.
Also, please don't tell me its depression causing this extreme laziness. I was way more motivated when I was depressed. These antipsychotics do the trick in relieving my bipolar symptoms, but I cant get a thing done. ps: I also tried all the other atypicals, Zyprexa, Respiradal, Seroquil, and they all totally unmotivate me.

 

Cathy, 

It does sound as though you are in a bind.  You listed Zyprexa, Risperdal, and Seroquel, but I am wondering if you have tried either Abilify or Geodon.  They may have a less negative effect on your energy levels.  Another possibility is trying a mood stabilizer with a smaller dose of your current antipsychotic to see if that will improve your motivation issues.  Have you been on a stimulant such as Adderall or Provigil?  Sometimes that will help with drive/motivation.  Also the older antipsychotics such as Haldol, Prolixin, or Trilafon could be useful but they do have higher risks of muscular side effects.  And lastly a round of ECT may be a worthwhile consideration.    

Dr Plyler

 
Published in May, 1011

 

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